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European Heart Journal Advance Access originally published online on November 29, 2008
European Heart Journal 2009 30(2):135-138; doi:10.1093/eurheartj/ehn517
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Published by Oxford University Press on behalf of the European Society of Cardiology 2008
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that the original authorship is properly and fully attributed; the Journal, Learned Society and Oxford University Press are attributed as the original place of publication with correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

Interpreting troponin elevations: do we need multiple diagnoses?

Gordon L. Pierpont1,2,* and Edward O. McFalls1,2

1 Cardiology Division, Minneapolis Veterans Administration Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
2 Cardiology Division, Department of Medicine, University of Minnesota, Minneapolis, MN, USA

Received 31 July 2008; accepted 23 October 2008; online publish-ahead-of-print 29 November 2008.

* Corresponding author. Tel: +1 612 467 3670, Fax: +1 612 970 5899, Email: pierp002@umn.edu

Key Words: Myocardial infarction • Troponin

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 150 words of the full text of this article appear below.

The expanded ability to detect myocardial injury using very sensitive and specific biomarker assays has been a major factor in the evolution of the definition of acute myocardial infarction (MI). This is clearly evident in the ‘Universal Definition of Myocardial Infarction’ recently developed by a joint task force of experts on behalf of the ESC, ACCF, AHA, and WHF (European Society of Cardiology, American College of Cardiology Foundation, American Heart Association, and World Heart Federation).1 In a clinical setting consistent with myocardial ischaemia, criteria are presented for defining acute MI that include a rise and/or fall in cardiac biomarkers together with symptoms of ischaemia, and/or appropriate ECG changes, and/or imaging evidence of a new regional wall motion abnormality or loss of myocardium. The . . . [Full Text of this Article]


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