Skip Navigation



European Heart Journal Advance Access published online on December 7, 2004
European Heart Journal, doi:10.1093/eurheartj/ehi024
This Article
Right arrow Full Text (Rapid PDF)
Right arrow All Versions of this Article:
26/2/180    most recent
ehi024v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Chiappini, B.
Right arrow Articles by Di Bartolomeo, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chiappini, B.
Right arrow Articles by Di Bartolomeo, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

European Heart Journal © The European Society of Cardiology 2004; all rights reserved.

Clinical research

Early and late outcomes of acute type A aortic dissection: analysis of risk factors in 487 consecutive patients

Bruno Chiappini 1*, Marc Schepens 2, Erwin Tan 2, Andrea Dell' Amore 1, Wim Morshuis 2, Karl Dossche 2, Marcello Bergonzini 1, Nicola Camurri 1, Letizia Bacchi Reggiani 1, Giuseppe Marinelli 1, and Roberto Di Bartolomeo 1

1 Department of Cardiovascular Surgery, Policlinico S.Orsola-Malpighi, via Massarenti 9, 40138 Bologna, Italy
2 Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands

* To whom correspondence should be addressed.
Bruno Chiappini, E-mail: bruno_chiappini{at}hotmail.com


  Abstract

Aims The purpose of this retrospective study was to assess the risk factors for the early and late outcome of the surgical treatment of acute type A aortic dissection, in terms of mortality and morbidity.

Methods and results From 1976 to 2003, 487 patients with acute type A aortic dissection treated surgically were enrolled. Twenty-five pre-operative and intra-operative variables were analysed to identify conditions influencing early and late morbidity and early mortality. The in-hospital mortality rate including operative death was 22% (107 patients). Multivariable analysis indicated that pre-existing cardiac disease (RR = 3.7, 95% CI = 1.8-7.4) and cardiopulmonary resuscitation (RR = 6.8, 95% CI = 2.3-20.2) were independent predictors of in-hospital death. The causes of in-hospital mortality were low cardiac output in 32 patients (6.6%), major brain damage in 24 patients (5.9%), haemorrhage in 11 patients (2.2%), sepsis in nine patients (1.8%), visceral ischaemia in eight patients (1.6%), multiple organ failure in seven patients (1.4%), rupture of the thoracic aorta in six patients (1.2%), respiratory failure in six patients (1.2%), and four intra-operative deaths. The follow-up was 100% complete. The actuarial survival was 94.9 ± 1.2% and 88.1 ± 2.6%, at 5 and 10 years, respectively.

Conclusions Patients' pre-operative co-morbidities and dissection-related complications significantly affect early and late survival and morbidity after surgical treatment of acute type A aortic dissection.

Keywords: Aortic dissection; Aorta; Surgery.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 CirculationHome page
L. A. Pape, T. T. Tsai, E. M. Isselbacher, J. K. Oh, P. T. O'Gara, A. Evangelista, R. Fattori, G. Meinhardt, S. Trimarchi, E. Bossone, et al.
Aortic Diameter >=5.5 cm Is Not a Good Predictor of Type A Aortic Dissection: Observations From the International Registry of Acute Aortic Dissection (IRAD)
Circulation, September 4, 2007; 116(10): 1120 - 1127.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. Nakajima, K. Kawazoe, T. Kataoka, H. Kin, T. Kazui, H. Okabayashi, and H. Niinuma
Midterm Results of Aortic Repair Using a Fabric Neomedia and Fibrin Glue for Type A Acute Aortic Dissection
Ann. Thorac. Surg., May 1, 2007; 83(5): 1615 - 1620.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. T. Tsai, R. Fattori, S. Trimarchi, E. Isselbacher, T. Myrmel, A. Evangelista, S. Hutchison, U. Sechtem, J. V. Cooper, D. E. Smith, et al.
Long-Term Survival in Patients Presenting With Type B Acute Aortic Dissection: Insights From the International Registry of Acute Aortic Dissection
Circulation, November 21, 2006; 114(21): 2226 - 2231.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. T. Tsai, A. Evangelista, C. A. Nienaber, S. Trimarchi, U. Sechtem, R. Fattori, T. Myrmel, L. Pape, J. V. Cooper, D. E. Smith, et al.
Long-Term Survival in Patients Presenting With Type A Acute Aortic Dissection: Insights from the International Registry of Acute Aortic Dissection (IRAD)
Circulation, July 4, 2006; 114(1_suppl): I-350 - I-356.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Pocar, D. Passolunghi, A. Moneta, R. Mattioli, and F. Donatelli
Coma Might Not Preclude Emergency Operation in Acute Aortic Dissection
Ann. Thorac. Surg., April 1, 2006; 81(4): 1348 - 1351.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.