Skip Navigation



European Heart Journal Advance Access published online on January 26, 2005
European Heart Journal, doi:10.1093/eurheartj/ehi101
This Article
Right arrow Full Text (Rapid PDF)
Right arrow All Versions of this Article:
26/8/755    most recent
ehi101v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bauer, A.
Right arrow Articles by Schmidt, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bauer, A.
Right arrow Articles by Schmidt, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

European Heart Journal © The European Society of Cardiology 2005; all rights reserved

Clinical research

Reduced prognostic power of ventricular late potentials in post-infarction patients of the reperfusion era

Axel Bauer 1, Przemyslaw Guzik 2, Petra Barthel 1, Raphael Schneider 1, Kurt Ulm 3, Mari A. Watanabe 4, and Georg Schmidt 1*

1 1. Medizinische Klinik der Technischen Universität München, Ismaninger Strasse 22, 81675 München, Germany
2 Department of Cardiology, University School of Medical Sciences, Poznan, Poland
3 Institut für Medizinische Statistik und Epidemiologie der Technischen Universität München, Germany
4 Department of Pharmacological and Physiological Science, St Louis University School of Medicine, St Louis, MO, USA

* To whom correspondence should be addressed.
Georg Schmidt, E-mail: gschmidt{at}tum.de


  Abstract

Aims To test the prognostic value of ventricular late potentials (LPs) in a large cohort of post-infarction patients in the modern reperfusion era.

Methods and results 1800 consecutive survivors of acute myocardial infarction in sinus rhythm and under 76 years of age were enrolled. Many (99%) of the patients received reperfusion/revascularization therapy (91% percutaneous coronary intervention) and up-to-date pharmacological treatment (99% aspirin, 93% beta-blockers, 90% ACE-inhibitors, and 85% statins). LPs were calculated in 968 patients and found to be present in 90 (9.3%). The primary endpoint was the composite of cardiac death and serious arrhythmic events. The secondary endpoint was the composite of sudden cardiac death and serious arrhythmic events. During follow-up (median 34 months), 26 patients reached the primary endpoint. The presence of LPs was not significantly associated with the primary endpoint in univariable or multivariable analysis. In contrast, low (≤30%) left ventricular ejection fraction (hazard ratio 9.6, 95% confidence interval 4.1-22.4), heart rate turbulence category 2 (7.5, 2.4-23.9) and category 1 (5.3, 1.9-14.9) were significant predictors in both univariable and multivariable analysis.

Conclusion Ventricular LPs are of limited use for risk stratification in unselected post-infarction patients in the modern reperfusion era.

Keywords: Ventricular late potentials; Mortality; Myocardial infarction.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 ESC Textbook of Cardiovascular MedicineHome page
F. G. Cosío, J.#x. Palacios, A.#x.;n Pastor, and A. Núñez
CHAPTER 2 The Electrocardiogram
ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
N Elgarhi, J Kreuz, O Balta, G Nickenig, H Hoium, T Lewalter, and J O. Schwab
Significance of Wedensky Modulation testing in the evaluation of non-invasive risk stratification for ventricular tachyarrhythmia in patients with coronary artery disease and implantable cardioverter-defibrillator
Heart, April 1, 2008; 94(4): e16 - e16.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
D. V. Exner, K. M. Kavanagh, M. P. Slawnych, L. B. Mitchell, D. Ramadan, S. G. Aggarwal, C. Noullett, A. Van Schaik, R. T. Mitchell, M. A. Shibata, et al.
Noninvasive Risk Assessment Early After a Myocardial Infarction: The REFINE Study
J. Am. Coll. Cardiol., December 11, 2007; 50(24): 2275 - 2284.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Sleight
New Methods for Risk Stratification in Patients After Myocardial Infarction: Autonomic Control and Substrate Sensitivity
J. Am. Coll. Cardiol., December 11, 2007; 50(24): 2291 - 2293.
[Full Text] [PDF]

Home page
 Br. J. Sports. Med.Home page
A. D'Andrea, P. Caso, G. Salerno, R. Scarafile, G. De Corato, C. Mita, G. Di Salvo, S. Severino, S. Cuomo, B. Liccardo, et al.
Left ventricular early myocardial dysfunction after chronic misuse of anabolic androgenic steroids: a Doppler myocardial and strain imaging analysis * COMMENTARY
Br. J. Sports Med., March 1, 2007; 41(3): 149 - 155.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
A. Bauer, M. A. Watanabe, P. Barthel, R. Schneider, K. Ulm, and G. Schmidt
QRS duration and late mortality in unselected post-infarction patients of the revascularization era
Eur. Heart J., February 2, 2006; 27(4): 427 - 433.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
K. L. Lee and C.-P. Lau
The use of signal-averaged electrocardiogram in risk stratification after acute myocardial infarction in the modern era
Eur. Heart J., April 2, 2005; 26(8): 747 - 748.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.