European Heart Journal Advance Access published online on March 30, 2005
European Heart Journal, doi:10.1093/eurheartj/ehi182
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Department of Cardiothoracic Surgery and Anaesthesiology, Karolinska University Hospital, S-171 76 Stockholm, Sweden
* To whom correspondence should be addressed. Aims Impaired fasting glucose (IFG) below the diagnostic threshold for diabetes mellitus (DM) is associated with macrovascular pathology and increased mortality after percutaneous coronary interventions. The study goal was to determine whether pre-operative fasting blood glucose (fB-glu) is associated with an increased mortality after coronary artery bypass grafting (CABG). Methods and results During 2001-03, 1895 patients underwent primary CABG [clinical DM (CDM) in 440/1895; complete data on fB-glu for n = 1375/1455]. Using pre-operative fB-glu, non-diabetics were categorized as having normal fB-glu (<5.6 mmol/L), IFG (5.6 Conclusion The elevated risk of death after CABG surgery known previously to be associated with CDM seems also to be shared by a group of similar size that includes patients with IFG and undiagnosed DM.
Received June 30, 2004
Revised December 12, 2004
Accepted January 27, 2005
Clinical research
Are even impaired fasting blood glucose levels preoperatively associated with increased mortality after CABG surgery?
2 Department of Epidemiology, Stockholm Centre for Public Health, Stockholm, Sweden
3 Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden; AstraZeneca Research & Development, Mölndal, Sweden
R.E. Anderson, E-mail: russell.anderson{at}kirurgi.ki.se
Abstract 
fB-glu < 6.1 mmol/L), or suspected DM (SDM) (
6.1 mmol/L). fB-glu was normal in 59%. The relative risks of 30 day and 1 year mortality compared with patients with normal fB-glu was 1.7 [95% confidence interval (CI): 0.5-5.5] and 2.9 (CI: 0.8-11.2) with IFG, 2.8 (CI: 1.1-7.2) and 1.9 (CI: 0.5-6.3) with SDM vs. 1.8 (CI: 0.8-4.0) and 1.6 (CI: 0.6-4.3) if CDM, respectively. The receiver operator characteristic area for the continuous variable fB-glu and 1 year mortality was 0.65 (P = 0.002).
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  T. Alserius, N. Hammar, T. Nordqvist, and T. Ivert Improved survival after coronary artery bypass grafting has not influenced the mortality disadvantage in patients with diabetes mellitus. J. Thorac. Cardiovasc. Surg., November 1, 2009; 138(5): 1115 - 1122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. L. Lazar Uric acid levels and outcomes from coronary artery bypass grafting: Is it the chicken or the egg? J. Thorac. Cardiovasc. Surg., July 1, 2009; 138(1): 8 - 8. [Full Text] [PDF]
|
|
|
|
 |
|
 R. E Anderson, K. Brismar, and T. Ivert Only a minority of patients referred for elective coronary artery bypass surgery have risk factors diagnosed and treated according to established guidelines Diabetes and Vascular Disease Research, June 1, 2007; 4(2): 112 - 116. [Abstract] [PDF]
|
|
|
|
 |
|
 P. F. White, H. Kehlet, J. M. Neal, T. Schricker, D. B. Carr, F. Carli, and the Fast-Track Surgery Study Group The Role of the Anesthesiologist in Fast-Track Surgery: From Multimodal Analgesia to Perioperative Medical Care Anesth. Analg., June 1, 2007; 104(6): 1380 - 1396. [Abstract] [Full Text] [PDF]
|
|