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European Heart Journal Advance Access published online on November 11, 2005

European Heart Journal, doi:10.1093/eurheartj/ehi630
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European Heart Journal © The European Society of Cardiology 2005; all rights reserved
Received June 13, 2005
Revised October 6, 2005
Accepted October 13, 2005

Clinical research

Coronary heart disease: from a disease of middle-aged men in the late 1970s to a disease of elderly women in the 2000s

Anna Kattainen 1*, Veikko Salomaa 2, Tommi Härkänen 1, Antti Jula 1, Risto Kaaja 3, Y. Antero Kesäniemi 4, Mika Kähönen 5, Leena Moilanen 6, Markku S. Nieminen 7, Arpo Aromaa 1, and Antti Reunanen 1

1 Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, FI-00300 Helsinki, Finland
2 Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
3 Department of Obstetrics and Gynaecology, University Central Hospital, Helsinki, Finland
4 Department of Internal Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland
5 Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland
6 Department of Medicine, Kuopio University Hospital, Kuopio, Finland
7 Division of Cardiology, University Central Hospital, Helsinki, Finland

* To whom correspondence should be addressed.
Anna Kattainen, E-mail: anna.kattainen{at}ktl.fi


   Abstract

Aims To analyse secular changes in the prevalence of coronary heart disease (CHD) and to assess changes in the burden of CHD at population level.

Methods and results Data were used from two large cross-sectional health examination surveys representing the entire Finnish adult population in 1980 and 2000. In the 1978-80 survey, the sample covered 5101 individuals aged ≥ 45, of whom 88% participated. The 2000-2001 survey comprised 5310 individuals in the same age range. Participation rate in the health examination was 87%. Prevalence of CHD decreased in men and women under the age of 65 and increased among those aged ≥ 75. Prevalence of large Q-waves indicating previous myocardial infarction decreased in all male age groups and in women aged 65-74. The total estimated number of persons with CHD increased by 18% (95% CI = 6-30) during the past 20 years in Finland. In 1980, the most dominant CHD group was men aged 45-64, whereas in 2000, women aged ≥ 75 comprised the largest CHD group.

Conclusion Although the prevalence of CHD has decreased among middle-aged persons, the number of CHD cases has increased during the past 20 years in Finland.

Keywords: Coronary disease; Angina; Myocardial infarction; Sex; Epidemiology.
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