European Heart Journal Advance Access published online on March 9, 2006
European Heart Journal, doi:10.1093/eurheartj/ehi824
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1 Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
* To whom correspondence should be addressed. Aims The aim of this study was to evaluate the diagnostic accuracy in the assessment of coronary artery bypass grafts using 64-slice computed tomography (CT) technology. Methods and results CT coronary angiography was performed for 96 bypasses in 31 patients with suspected coronary artery disease using a Siemens Sensation 64-slice CT-scanner and compared with invasive coronary angiography (ICA). Patients with an irregular or fast heart rate despite Conclusion State-of-the-art 64-slice CT coronary angiography demonstrates high diagnostic accuracy in the assessment of arterial and venous bypass graft stenoses.
Received July 18, 2005
Revised January 20, 2006
Accepted February 9, 2006
Clinical research
Initial experience with 64-slice cardiac CT: non-invasive visualization of coronary artery bypass grafts
Gregor Pache 1 *,
Ulrich Saueressig 1,
Alex Frydrychowicz 1,
Daniela Foell 2,
Nadir Ghanem 1,
Elmar Kotter 1,
Annette Geibel-Zehender 2,
Christoph Bode 2,
Mathias Langer 1,
and
Thorsten Bley 1
2 Department of Cardiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
Gregor Pache, E-mail: pache{at}mrs1.ukl.uni-freiburg.de
Abstract 
-blocker administration were not excluded from the study. All bypass grafts and 94% of the distal bypass anastomoses could be visualized by CT, non-evaluable distal arterial anastomoses were either due to clip material or calcification artefacts. Forty-two bypass graft occlusions and three significant stenoses were detected by CT and confirmed by ICA. Two venous grafts were missed and one arterial graft was not evaluable with ICA, but both were clearly depicted by multi-slice CT. One false negative and two false positive CT-findings resulted in a sensitivity of 97.8%, a specificity of 89.3%, a positive predictive value of 90%, and a negative predictive value of 97.7%.
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