Skip Navigation



European Heart Journal Advance Access published online on September 26, 2006
European Heart Journal, doi:10.1093/eurheartj/ehl278
This Article
Right arrow Full Text (Rapid PDF)
Right arrow All Versions of this Article:
27/22/2696    most recent
ehl278v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Hoffmann, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hoffmann, B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

European Heart Journal © The European Society of Cardiology 2006; all rights reserved
Received March 3, 2006
Revised September 7, 2006
Accepted September 11, 2006

Preclinical research

Residence close to high traffic and prevalence of coronary heart disease

Barbara Hoffmann 1 *, Susanne Moebus 1, Andreas Stang 2, Eva-Maria Beck 1, Nico Dragano 3, Stephan Möhlenkamp 4, Axel Schmermund 4, Michael Memmesheimer 5, Klaus Mann 6, Raimund Erbel 4, and Karl-Heinz Jöckel 1, on behalf of the Heinz Nixdorf RECALL Study Investigative Group

1 Institute for Medical Informatics, Biometry and Epidemiology, University Hospital, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany
2 Institute of Medical Epidemiology, Biometry and Informatics, Medical Faculty, Martin-Luther-University of Halle-Wittenberg, Halle, Germany
3 Institute of Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany
4 West German Heart Center Essen, University Hospital, University of Duisburg-Essen, Essen, Germany
5 Rhenish Institute for Environmental Research at the University of Cologne, Cologne, Germany
6 Department of Endocrinology, University Hospital, University of Duisburg-Essen, Essen, Germany

* To whom correspondence should be addressed.
Barbara Hoffmann, E-mail: barbara.hoffmann{at}uk-essen.de


  Abstract

Aims Long-term exposure to urban air pollution may accelerate atherogenesis and increase cardiopulmonary mortality. We aim to examine the relationship between the long-term residential exposure to traffic and prevalence of coronary heart disease (CHD).

Methods and results We used baseline data from the German Heinz Nixdorf RECALL study, a population-based, prospective cohort study. For 3399 participants from two cities, we assessed the long-term personal traffic exposure and background air pollution, comparing residents living within 150 m of major roads with those living further away. The principal outcome variable was clinically manifest CHD. We evaluated the association with multivariable logistic regression, controlling for background air pollution and individual level risk factors. Of 3399 participants, 242 (7.1%) had CHD. The crude odds ratio (OR) for prevalence of CHD at high traffic exposure was significantly elevated (1.62, 95%CI 1.12-2.34) and rose to 1.85 (95%CI 1.21-2.84) after adjusting for cardiovascular risk factors and background air pollution. Subgroup analysis showed stronger effects for men (OR 2.33, 95%CI 1.44-3.78), participants younger than 60 years (OR 2.67, 95%CI 1.24-5.74) and never-smokers (OR 2.72, 95%CI 1.40-5.29).

Conclusion This study provides epidemiological evidence that the long-term exposure to traffic-related emissions may be an important risk factor for CHD.

Keywords: Coronary disease; Epidemiology; Risk factors; Air pollution; Traffic emissions.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Occup. Environ. Med.Home page
N Dragano, B Hoffmann, S Moebus, S Mohlenkamp, A Stang, P E Verde, K-H Jockel, R Erbel, J Siegrist, and on behalf of the Heinz Nixdorf Recall Study Invest
Traffic exposure and subclinical cardiovascular disease: is the association modified by socioeconomic characteristics of individuals and neighbourhoods? Results from a multilevel study in an urban region
Occup. Environ. Med., September 1, 2009; 66(9): 628 - 635.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
A. Baccarelli, I. Martinelli, V. Pegoraro, S. Melly, P. Grillo, A. Zanobetti, L. Hou, P. A. Bertazzi, P. M. Mannucci, and J. Schwartz
Living Near Major Traffic Roads and Risk of Deep Vein Thrombosis
Circulation, June 23, 2009; 119(24): 3118 - 3124.
[Abstract] [Full Text] [PDF]

Home page
 Occup. Environ. Med.Home page
R Beelen, G Hoek, D Houthuijs, P A van den Brandt, R A Goldbohm, P Fischer, L J Schouten, B Armstrong, and B Brunekreef
The joint association of air pollution and noise from road traffic with cardiovascular mortality in a cohort study
Occup. Environ. Med., April 1, 2009; 66(4): 243 - 250.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
H. Kan, G. Heiss, K. M Rose, E. Whitsel, F. Lurmann, and S. J London
Traffic exposure and lung function in adults: the Atherosclerosis Risk in Communities study
Thorax, October 1, 2007; 62(10): 873 - 879.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
B. Hoffmann, S. Moebus, S. Mohlenkamp, A. Stang, N. Lehmann, N. Dragano, A. Schmermund, M. Memmesheimer, K. Mann, R. Erbel, et al.
Residential Exposure to Traffic Is Associated With Coronary Atherosclerosis
Circulation, July 31, 2007; 116(5): 489 - 496.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
B. Brunekreef
Traffic and the heart
Eur. Heart J., November 2, 2006; 27(22): 2621 - 2622.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.