European Heart Journal Advance Access published online on November 5, 2007
European Heart Journal, doi:10.1093/eurheartj/ehl399
© The European Society of Cardiology 2006. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
When renal and cardiac insufficiencies intersect: is there a role for natriuretic peptide testing in the ‘cardio-renal syndrome’?
1 Department of Cardiology, University Hospital Maastricht, The Netherlands
2 Division of Cardiology, Massachusetts General Hospital, Yawkey 5800, 55 Fruit Street, Boston, MA 02114, USA
* Corresponding author. Tel: +1 617 726 3443; fax: +1 617 643 1620. E-mail address: jjanuzzi@partners.org
This editorial refers to ‘Renal dysfunction, as measured by the modification of diet in renal disease (MDRD) equations, and outcome in patients with advanced heart failure’ by R.S. Gardner et al., doi:10.1093/eurheartj/ehm480
| The first 10% of the full text of this article appears below. |
In this issue of the European Heart Journal, Gardner et al.,1 report that NT-proBNP maintains strong prognosis in heart failure (HF) patients with renal impairment. This is an interesting contribution to the debate about the utility of NT-proBNP in renal impairment; chronic kidney disease is an important complication in patients suffering from HF, while there is often heated discussion about the usefulness of BNP and NT-proBNP measurement in patients with renal insufficiency.
Because of considerable overlap of risk factors and a myriad of pathophysiologic mechanisms, insufficiencies of the renal and cardiac system are tightly related.2 Furthermore, when HF is complicated by renal impairment, the prognosis of the patient worsens dramatically.3 Vice versa, patients with worse renal function are more likely to have heart disease, and those patients combining heart disease and renal dysfunction are more likely to suffer greater rates of
CiteULike 
Connotea 
Del.icio.us What's this?
Related articles in EHJ:
- Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure
- Roy S. Gardner, Kwok S. Chong, Eileen O’Meara, Alan Jardine, Ian Ford, and Theresa A. McDonagh
EHJ 2007 28: 3027-3033.[Abstract] [FREE Full Text]
This article has been cited by other articles:
|
|
 |
|
  U. Alehagen, U. Dahlstrom, and T. L. Lindahl Cystatin C and NT-proBNP, a powerful combination of biomarkers for predicting cardiovascular mortality in elderly patients with heart failure: results from a 10-year study in primary care Eur J Heart Fail, April 1, 2009; 11(4): 354 - 360. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Tagore, L. H. Ling, H. Yang, H.-Y. Daw, Y.-H. Chan, and S. K. Sethi Natriuretic Peptides in Chronic Kidney Disease Clin. J. Am. Soc. Nephrol., November 1, 2008; 3(6): 1644 - 1651. [Abstract] [Full Text] [PDF]
|
|