European Heart Journal Advance Access published online on January 22, 2007
European Heart Journal, doi:10.1093/eurheartj/ehl475
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
The joint associations of occupational, commuting, and leisure-time physical activity, and the Framingham risk score on the 10-year risk of coronary heart disease
1 Department of Health Promotion and Chronic Diseases Prevention, National Public Health Institute, Mannerheimintie 166, FIN-00300 Helsinki, Finland
2 Department of Public Health, University of Helsinki, Helsinki, Finland
3 South Ostrobothnia Central Hospital, Seinäjoki, Finland
4 Tampere School of Public Health, University of Tampere, Tampere, Finland
Received 19 September 2006; revised 22 November 2006; accepted 21 December 2006.
* Corresponding author. Tel: +358 9 19127366; fax: +358 9 19127313. E-mail address: hu.gang{at}ktl.fi
Aims To determine joint associations of different kinds of physical activity and the Framingham risk score (FRS) with the 10-year risk of coronary heart disease (CHD) events.
Methods and results Study cohorts included 41 053 Finnish participants aged 25–64 years without history of CHD and stroke. The multivariable-adjusted 10-year hazard ratios (HRs) of coronary events associated with low, moderate, and high occupational physical activity were 1.00, 0.66, and 0.74 (Ptrend < 0.001) for men, and 1.00, 0.53, and 0.58 (Ptrend < 0.001) for women, respectively. The multivariable-adjusted 10-year HRs of coronary events associated with low, moderate, and high leisure-time physical activity were 1.00, 0.97, and 0.66 (Ptrend = 0.002) for men, and 1.00, 0.74, and 0.54 (Ptrend = 0.003) for women, respectively. Active commuting had a significant inverse association with 10-year risk of coronary events in women only. The FRS predicted 10-year risk of coronary events among both men and women. The protective effects of occupational, commuting, or leisure-time physical activity were consistent in subjects with a very low ( < 6 % ), low (6–9 % ), intermediate (10–19 % ), or high ( 
20 % ) risk of the FRS.
Conclusion Moderate or high levels of occupational or leisure-time physical activity among both men and women, and daily walking or cycling to and from work among women are associated with a reduced 10-year risk of CHD events. These favourable effects of physical activity on CHD risk are observed at all levels of CHD risk based on FRS assessment.
Key Words: Exercise • Risk factors • Cardiovascular diseases
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  G. Hu, P. Jousilahti, J. Tuomilehto, R. Antikainen, J. Sundvall, and V. Salomaa Association of Serum C-Reactive Protein Level with Sex-Specific Type 2 Diabetes Risk: A Prospective Finnish Study J. Clin. Endocrinol. Metab., June 1, 2009; 94(6): 2099 - 2105. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Borodulin, T. Laatikainen, A. Juolevi, and P. Jousilahti Thirty-year trends of physical activity in relation to age, calendar time and birth cohort in Finnish adults Eur J Public Health, June 1, 2008; 18(3): 339 - 344. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Hu, R. Antikainen, P. Jousilahti, M. Kivipelto, and J. Tuomilehto Total cholesterol and the risk of Parkinson disease Neurology, May 20, 2008; 70(21): 1972 - 1979. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sanz, P. R. Moreno, and V. Fuster The year in atherothrombosis. J. Am. Coll. Cardiol., March 4, 2008; 51(9): 944 - 955. [Full Text] [PDF]
|
|
|
|
 |
|
 R. J Kaaja Metabolic syndrome and the menopause Menopause Int, March 1, 2008; 14(1): 21 - 25. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Hu, J. Lindstrom, P. Jousilahti, M. Peltonen, L. Sjoberg, R. Kaaja, J. Sundvall, and J. Tuomilehto The Increasing Prevalence of Metabolic Syndrome among Finnish Men and Women over a Decade J. Clin. Endocrinol. Metab., March 1, 2008; 93(3): 832 - 836. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Hu, P. Jousilahti, and J. Tuomilehto Joint effects of history of hypertension at baseline and type 2 diabetes at baseline and during follow-up on the risk of coronary heart disease Eur. Heart J., December 2, 2007; 28(24): 3059 - 3066. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Hu, P. Jousilahti, A. Nissinen, S. Bidel, R. Antikainen, and J. Tuomilehto Coffee consumption and the incidence of antihypertensive drug treatment in Finnish men and women Am. J. Clinical Nutrition, August 1, 2007; 86(2): 457 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Hu, J. Tuomilehto, K. Silventoinen, C. Sarti, S. Mannisto, and P. Jousilahti Body Mass Index, Waist Circumference, and Waist-Hip Ratio on the Risk of Total and Type-Specific Stroke Arch Intern Med, July 9, 2007; 167(13): 1420 - 1427. [Abstract] [Full Text] [PDF]
|
|