Skip Navigation



European Heart Journal Advance Access published online on March 29, 2007
European Heart Journal, doi:10.1093/eurheartj/ehm015
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
28/8/929    most recent
ehm015v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Jaumdally, R.
Right arrow Articles by Lip, G. Y.H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jaumdally, R.
Right arrow Articles by Lip, G. Y.H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Coronary sinus blood sampling: an insight into local cardiac pathophysiology and treatment?

Rumi Jaumdally, Chetan Varma, Robert J Macfadyen and Gregory Y.H. Lip*

Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK

Received 27 November 2006; revised 9 February 2007; accepted 15 February 2007.

* Corresponding author. Tel: +44 121 507 5080; fax: +44 121 554 4083; E-mail address: g.y.h.lip{at}bham.ac.uk

Atherosclerosis remains the underlying cause of cardiovascular disease and is a dynamic process involving inflammation, haemostasis, endothelial dysfunction, and angiogenesis. Studies of circulating factors from peripheral blood can provide an insight into this pathophysiology but may remain indicative of a more generalized, systemic process. More localized interaction(s) within the heart may be better studied from coronary blood samples. Indeed, an increasing number of prospective studies show good correlation between indices of these processes and clinical outcomes. As local sampling offers a unique way of assessing the local cardiac milieu, this may prove useful in the monitoring of both local/systemic drug therapies and interventional technologies.

Key Words: Coronary sinus • Circulating factors • Myocardial ischaemia


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Lab MedHome page
K. Hoetzenecker, C. Adlbrecht, M. Lichtenauer, S. Hacker, W. Hoetzenecker, A. Mangold, S. Nickl, A. Mitterbauer, M. Zimmermann, I. M. Lang, et al.
Levels of sCD40, sCD40L, TNF{alpha}, and TNF-RI in the Culprit Coronary Artery During Myocardial Infarction
Lab Med, November 1, 2009; 40(11): 660 - 664.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.