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European Heart Journal Advance Access published online on November 6, 2007
European Heart Journal, doi:10.1093/eurheartj/ehm409
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Ability of DNase I activity to detect myocardial ischaemia in vasospastic angina—a view through a monocle?

Evangelos Giannitsis and Hugo A. Katus*

Medizinische Universitätsklinik Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany

* Corresponding author. Tel: +49-6221-56-8670; fax: +49-6221-5516. E-mail address: hugo_katus@med.uni-heidelberg.de

This editorial refers to ‘Serum deoxyribonuclease I activity can be used as a novel marker of transient myocardial ischaemia: results in vasospastic angina pectoris induced by provocation test’ by N. Morikawa et al., doi:10.1093/eurheartj/ehm483

The first 10% of the full text of this article appears below.

The detection of myocardial ischaemia earlier or in the absence of myocardial infarction is challenging and has the potential to improve the process of triage of patients with acute coronary syndrome (ACS).

Still, cardiac troponins represent the gold standard for the biochemical diagnosis of acute myocardial infarction, for the classification and risk stratification of ACS, and for the objective guidance of anti-ischaemic therapies.1 New biomarkers are frequently pushed forward with the claim to be more specific, more sensitive, or to appear earlier in blood than cardiac troponins. Until now, all of these . . . [Full Text of this Article]


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Serum deoxyribonuclease I activity can be used as a novel marker of transient myocardial ischaemia: results in vasospastic angina pectoris induced by provocation test
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EHJ 2007 28: 2992-2997. [Abstract] [FREE Full Text]