European Heart Journal Advance Access published online on September 28, 2007
European Heart Journal, doi:10.1093/eurheartj/ehm434
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
The apoB/apoA-I ratio and insulin resistance: sorting out the metabolic syndrome
Mike Rosenbloom Laboratory for Cardiovascular Research, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Avenue West Montreal, Quebec H3A 1A1, Canada
Corresponding author. Tel: +1 514-934-1934 ext. 34637; fax: +1 514-843-2843. E- mail address: allansniderman@hotmail.com
This editorial refers to ApoB/ApoA-I ratio: an independent predictor of insulin resistance in US non-diabetic subjects by J. Sierra-Johnson et al., doi:10.1093/eurheartj/ehm360
| The first 10% of the full text of this article appears below. |
Sierra-Johnson et al.1 demonstrate that the apoB/apoA-I ratio is an independent predictor of insulin resistance in non-diabetic Americans. This was the case in men and women and was independent of the traditional risk factors, components of the metabolic syndrome, and inflammatory risk markers such as C-reactive protein (CRP). The strengths of this study are the meticulous construction of the NHANES database on which it is based and the meticulous analysis of it that was undertaken. Previously, these authors and others have shown that the apoB/apoA-I ratio becomes progressively more abnormal as the number of components of the metabolic syndrome increases2 and that apoB is more closely tied to dysglycaemia and inflammation than low-density lipoprotein (LDL) cholesterol or non-high-density
![]()
CiteULike
Connotea
Del.icio.us What's this?
Related articles in EHJ:
- ApoB/apoA-I ratio: an independent predictor of insulin resistance in US non-diabetic subjects
- Justo Sierra-Johnson, Abel Romero-Corral, Virend K. Somers, Francisco Lopez-Jimenez, Göran Walldius, Anders Hamsten, Mai-Lis Hellénius, and Rachel M. Fisher
EHJ 2007 28: 2637-2643.[Abstract] [FREE Full Text]
This article has been cited by other articles:
![]() |
J. Sierra-Johnson, R. M. Fisher, A. Romero-Corral, V. K. Somers, F. Lopez-Jimenez, J. Ohrvik, G. Walldius, M.-L. Hellenius, and A. Hamsten Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population Eur. Heart J., March 2, 2009; 30(6): 710 - 717. [Abstract] [Full Text] [PDF] |
||||
