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European Heart Journal Advance Access published online on October 17, 2007
European Heart Journal, doi:10.1093/eurheartj/ehm452
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

Annexin A5 and the failing heart; lost or found in translation?

Leonard Hofstra and Stephane Heymans*

Cardiovascular Research Institute Maastricht, Department of Cardiology, P Debeyelaan 25, 6202 AZ, Maastricht, The Netherlands

* Corresponding author. Tel: +31 43 3882949; fax: +31 43 3871055. E-mail address: s.heymans@cardio.unimaas.nl

This editorial refers to ‘Upregulation of myocardial Annexin A5 in hypertensive heart disease: association with systolic dysfunction’ by S. Ravassa et al., doi:10.1093/eurheartj/ehm370

The first 10% of the full text of this article appears below.

Heart failure is the number one reason for hospital admission in patients above 65 years of age. It is predicted that the number of heart failure patients will almost double in the next 20 years. Ischaemic and hypertensive heart disease are the major causes of this disabling disease. Approximately 22% of women and 46% of men who have had a myocardial infarction will develop heart failure within 6 years.1 Still, hypertension is a chief cause of cardiac failure: diastolic dysfunction accounts for >50% of all heart failure patients.2 In the world we live in, an increasing number of people become at risk of developing hypertension heart disease due to the epidemic proportions of obesity and the concomitant development of diabetes. The obesity epidemic is not restricted to countries . . . [Full Text of this Article]


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Related articles in EHJ:

Upregulation of myocardial Annexin A5 in hypertensive heart disease: association with systolic dysfunction
Susana Ravassa, Arantxa González, Begoña López, Javier Beaumont, Ramón Querejeta, Mariano Larman, and Javier Díez
EHJ 2007 28: 2785-2791. [Abstract] [FREE Full Text]