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European Heart Journal Advance Access published online on October 24, 2007
European Heart Journal, doi:10.1093/eurheartj/ehm474
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

DES or BMS in acute myocardial infarction?

Pieter J. Vlaar*, Bart J. G. L. de Smet and Felix Zijlstra

Department of Cardiology, University Medical Centre Groningen Thorax Centre, Groningen, The Netherlands

* Corresponding author. Tel: +31 50 3611413; fax: +31 50 3614391. E-mail address: p.j.j.vlaar@thorax.umcg.nl

This editorial refers to ‘Meta-analysis of randomized controlled trials on drug-eluting stents vs. bare-metal stents in patients with acute myocardial infarction’ by A. Kastrati et al. doi:10.1093/eurheartj/ehm402

The first 10% of the full text of this article appears below.

The prognosis of patients with acute myocardial infarction (AMI) has been considerably improved following the introduction of reperfusion therapies. The primary aim in the acute phase of an AMI is rapid and sustained restoration of blood flow through the infarct-related artery. When logistically feasible, primary percutaneous coronary intervention (PCI) has emerged as the preferred reperfusion modality. Compared with balloon angioplasty, implantation of a bare metal stent (BMS) results in a lower rate of reocclusion and restenosis. Nevertheless, rates of target vessel revascularization after BMS implantation in patients with AMI range from 7 to 15%.1,2

The clinical presentation of the restenotic process is most often recurrence of angina, and is usually . . . [Full Text of this Article]

Is the external validity of DES vs. BMS trials in acute myocardial infarction compromised?

Late and very late stent thrombosis (>1 or >3 years after implantation)

The clinical outcome of DES after 3–5 years

Cost–benefit ratio of DES

Conclusion


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Related articles in EHJ:

Meta-analysis of randomized trials on drug-eluting stents vs. bare-metal stents in patients with acute myocardial infarction
Adnan Kastrati, Alban Dibra, Christian Spaulding, Gerrit J. Laarman, Maurizio Menichelli, Marco Valgimigli, Emilio Di Lorenzo, Christoph Kaiser, Ilkka Tierala, Julinda Mehilli, Melchior Seyfarth, Olivier Varenne, Maurits T. Dirksen, Gianfranco Percoco, Attilio Varricchio, Undine Pittl, Mikko Syvänne, Maarten J. Suttorp, Roberto Violini, and Albert Schömig
EHJ 2007 28: 2706-2713. [Abstract] [FREE Full Text]  



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