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European Heart Journal Advance Access published online on February 12, 2008
European Heart Journal, doi:10.1093/eurheartj/ehm638
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Abdominal aorta aneurysm: an exceptional expression of atherosclerotic disease in type II diabetes

K. L. Rensing and Th. B. Twickler*

Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands

* Corresponding author: Tel: +31 20 566 5737, Fax: +31 20 566 9343, Email: t.b.twickler@amc.uva.nl

This editorial refers to ‘Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte–matrix interactions’ by J. Golledge et al. doi:10.1093/eurheartj/ehm557

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An aortic abdominal aneurysm (AAA) is a potentially lethal disease. In a population with one or multiple cardiovascular risk factors, its prevalence is estimated at 1.6% (aneurysm size >3 cm) and 0.5% (aneurysm size >4 cm), with a higher occurrence in male vs. female patients. In the presence of type II diabetes, the prevalence of all cardiovascular disease (including carotid stenosis, AAA, and peripheral artery disease) is doubled.1 The Veterans Affairs Cooperative Study Investigators study showed a higher prevalence of AAA in their screened population. In addition, a negative association was found between AAA and the presence of diabetes (with no difference in male vs. female).2 Despite the fact that AAA . . . [Full Text of this Article]


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Related articles in EHJ:

Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte–matrix interactions
Jonathan Golledge, Mirko Karan, Corey S. Moran, Juanita Muller, Paula Clancy, Anthony E. Dear, and Paul E. Norman
EHJ 2008 29: 665-672. [Abstract] [Full Text]