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European Heart Journal Advance Access published online on June 13, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn068
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Optimal treatment for in-stent restenosis after BMS—DES, coated balloon, or scalpel?

Debabrata Mukherjee*

Gill Heart Institute, University of Kentucky, Lexington, KY 40536-0200, USA

* Corresponding author. Tel: +1 859 323 5630, Fax: +1 859 323 6475. Email: Mukherjee@uky.edu

This editorial refers to ‘Two-year clinical outcomes after paclitaxel-eluting stent or brachytherapy treatment for bare metal stent restenosis: the TAXUS V ISR trial’{dagger} by S.G. Ellis et al., on page 1625

The first 10% of the full text of this article appears below.

The year 2007 saw a significant decrease in the usage of drug-eluting stents (DES)1 and a commensurate increase in the usage of bare metal stents (BMS) primarily because of concern about stent thrombosis with DES. As a result of increased use of BMS, we are likely to see more patients presenting with in-stent restenosis (ISR) after BMS, and determining the optimal treatment of these individuals becomes clinically relevant.

During the last decade, numerous modalities have been used to treat ISR after BMS, with only modest intermediate-term efficacy. These devices, including balloon angioplasty, atherectomy (directional, rotational, and laser), and repeat stenting (stent-in-stent), provided a high rate of immediate technical success and a low rate . . . [Full Text of this Article]


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Related articles in EHJ:

Two-year clinical outcomes after paclitaxel-eluting stent or brachytherapy treatment for bare metal stent restenosis: the TAXUS V ISR trial
Stephen G. Ellis, Charles D. O'Shaughnessy, Steven L. Martin, Kenneth Kent, Thomas McGarry, Mark A. Turco, Dean J. Kereiakes, Jeffrey J. Popma, Mark Friedman, Joerg Koglin, Gregg W. Stone, and for the TAXUS V ISR Investigators
EHJ 2008 29: 1625-1634. [Abstract] [FREE Full Text]