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European Heart Journal Advance Access published online on March 11, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn074
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Why do men and women differ in their risk of myocardial infarction?

Duncan J. Campbell*

St Vincent's Institute of Medical Research and the Department of Medicine, University of Melbourne, St Vincent's Hospital, Fitzroy, Victoria, Australia

* Corresponding author. Tel: + 61 3 9288 2480, Fax: + 61 3 9416 2676, Email: dcampbell@svi.edu.au

This editorial refers to ‘Risk factors for myocardial infarction in women and men: insights from the INTERHEART study’ by S.S. Anand et al., doi:10.1093/eurheartj/ehn018

The first 10% of the full text of this article appears below.

Cardiovascular disease is a global problem. To enable more effective prevention strategies for myocardial infarction (MI), the INTERHEART study looked for differences between countries, and between men and women, in risk factors for acute MI.1 It was a case–control study with 15 152 cases of acute MI and 14 820 controls from 262 centres from 52 countries. Information about nine risk factors was collected: smoking, self-reported hypertension and diabetes, measured waist/hip ratio, psychosocial factors, diet, physical activity, alcohol consumption, and measured apolipoprotein B/apolipoprotein A1 ratio.1 In their first report. the INTERHEART investigators concluded that these nine risk factors accounted for most of the risk for acute MI in both sexes, at all ages, and in all regions.1 When all nine risk factors were included in the analysis, the population-attributable risk for men ≤55 years was 93.1% and for . . . [Full Text of this Article]


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Related articles in EHJ:

Risk factors for myocardial infarction in women and men: insights from the INTERHEART study
Sonia S. Anand, Shofiqul Islam, Annika Rosengren, Maria Grazia Franzosi, Krisela Steyn, Afzal Hussein Yusufali, Matyas Keltai, Rafael Diaz, Sumathy Rangarajan, Salim Yusuf, and on behalf of the INTERHEART Investigators
EHJ 2008 29: 932-940. [Abstract] [FREE Full Text]