Skip Navigation



European Heart Journal Advance Access published online on April 7, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn139
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
29/9/1181    most recent
ehn139v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Nieuwlaat, R.
Right arrow Articles by Crijns, H. J.G.M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nieuwlaat, R.
Right arrow Articles by Crijns, H. J.G.M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on Atrial Fibrillation

Robby Nieuwlaat1,*, Martin H. Prins2, Jean-Yves Le Heuzey3, Panos E. Vardas4, Etienne Aliot5, Massimo Santini6, Stuart M. Cobbe7, Jos W.M.G. Widdershoven8, Leo H. Baur9, Samuel Lévy10 and Harry J.G.M. Crijns1

1 Department of Cardiology, University Hospital Maastricht, Maastricht, The Netherlands
2 Department of Clinical Epidemiology and Medical Technology Assessment, University Hospital Maastricht, Maastricht, The Netherlands
3 Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
4 Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, Greece
5 Department of Cardiology, University Hospital Nancy, Nancy, France
6 Department of Cardiology, San Filippo Neri Hospital, Rome, Italy
7 Department of Medical Cardiology, Royal Infirmary, Glasgow, UK
8 Department of Cardiology, TweeSteden Ziekenhuis, Tilburg, The Netherlands
9 Department of Cardiology, Atrium Medical Centre, Heerlen, The Netherlands
10 Division of Cardiology, Centre Hospitalier Universitaire Nord, Marseille, France

Received 18 January 2007; revised 20 February 2008; accepted 13 March 2008.

* Corresponding author. Tel: +31 43 3875053, Fax: +31 43 3875104, Email: nieuwlaatrobby{at}live.com.au

Aims: To gain insight in the prognosis and treatment of atrial fibrillation (AF) patients during 1-year follow-up in the Euro Heart Survey (EHS) on AF.

Methods and results: The EHS enrolled 5333 AF patients in 2003–2004. One-year follow-up data were available for 80%. Of first detected AF patients, 46% did not have a recurrence during 1 year, paroxysmal AF largely remained paroxysmal AF (80%), and 30% of persistent AF progressed to permanent AF. Many treatment changes occurred since baseline. Oral anticoagulation was started in 19% and discontinued in 16% of all patients. Of patients initially on rhythm control 27% did not receive rhythm control during follow-up, whereas 15% of patients initially on rate control received rhythm control. Mortality was highest in permanent AF (8.2%), but also substantial in first detected AF (5.7%). In multivariable analysis, sinus rhythm at baseline was associated with lower mortality, but no significant effect was observed regarding the application of either rhythm or rate control.

Conclusion: The EHS on AF provides unique prospective observational data on AF progression, long-term treatment, prognosis, and determinants of adverse outcome of the total clinical spectrum of AF in a European cardiology-based patient cohort.

Key Words: Atrial fibrillation • Mortality • Prognosis • Progression • Management • Anticoagulation • Rhythm control • Rate control


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur Heart JHome page
A. Shotan, M. Garty, D. S. Blondhein, S. R. Meisel, B. S. Lewis, M. Shochat, E. Grossman, A. Porath, V. Boyko, R. Zimlichman, et al.
Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS)
Eur. Heart J., October 15, 2009; (2009) ehp422v1.
[Abstract] [Full Text] [PDF]

Home page
 EuropaceHome page
R. Pisters, C. B. de Vos, R. Dennert, and H. J. Crijns
Undetected paroxysmal atrial fibrillation in chronic heart failure patients: is it clinically relevant to catch the atrial phantom?
Europace, October 1, 2009; 11(10): 1257 - 1259.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
D. J. Wilber
Pursuing sinus rhythm in patients with persistent atrial fibrillation: when is it too late?
J. Am. Coll. Cardiol., August 25, 2009; 54(9): 796 - 798.
[Full Text] [PDF]

Home page
 Circ Arrhythm ElectrophysiolHome page
M. R. Reynolds, P. Zimetbaum, M. E. Josephson, E. Ellis, T. Danilov, and D. J. Cohen
Cost-Effectiveness of Radiofrequency Catheter Ablation Compared With Antiarrhythmic Drug Therapy for Paroxysmal Atrial Fibrillation
Circ Arrhythm Electrophysiol, August 1, 2009; 2(4): 362 - 369.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Nieuwlaat, L. W. Eurlings, J. G. Cleland, S. M. Cobbe, P. E. Vardas, A. Capucci, J. L. Lopez-Sendon, J. G. Meeder, Y. M. Pinto, and H. J.G.M. Crijns
Atrial fibrillation and heart failure in cardiology practice: reciprocal impact and combined management from the perspective of atrial fibrillation: results of the Euro Heart Survey on atrial fibrillation.
J. Am. Coll. Cardiol., May 5, 2009; 53(18): 1690 - 1698.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.