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European Heart Journal Advance Access published online on June 5, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn238
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Non-invasive risk stratification in hypertrophic cardiomyopathy: don't throw out the baby with the bathwater

Srijita Sen-Chowdhry1,2 and William J. McKenna1,*

1 The Heart Hospital, University College London Hospitals NHS Trust and Institute of Cardiovascular Science, London, UK
2 Imperial College, London, UK

* Corresponding author. Tel: +44 2075738841, Fax: +44 2075738859, Email: william.mckenna@uclh.org

This editorial refers to ‘Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy’ by R.C. Suamarez et al. doi:10.1093/eurheartj/ehn111

The first 150 words of the full text of this article appear below.

Although historical accounts consistent with sudden cardiac death (SCD) date back to ancient times, only in the past quarter of a century has prevention of these events become possible. Growing understanding of underlying disease states, development of effective anti-arrhythmic therapy, and the advent of the implantable cardioverter-defibrillators (ICDs) have all contributed to realization of this goal. Nevertheless, prophylactic ICD placement in the inherited cardiovascular disease population to some extent represents a double-edged sword. On the one hand, averting SCD in individuals without debilitating symptoms or co-morbidities may yield an exceptional number of quality-adjusted life years. Conversely, the present knowledge gap regarding the consequences of extended device therapy is of particular relevance in young patients in whom the aim is to achieve normal life expectancy. Increasing awareness that ICDs are not a trouble-free panacea for all patients with SCD syndromes1,2 has underscored the importance of reliable risk prediction.

Hypertrophic cardiomyopathy (HCM) . . . [Full Text of this Article]


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Related articles in EHJ:

Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy
Richard C. Saumarez, Mariusz Pytkowski, Maciej Sterlinski, John P. Bourke, Jonathan R. Clague, Stuart M. Cobbe, Derek T. Connelly, Michael J. Griffith, Pascal P. McKeown, Karen McLeod, John M. Morgan, Nicolas Sadoul, Lidia Chojnowska, Christopher L.-H. Huang, and Andrew A. Grace
EHJ 2008 29: 1653-1661. [Abstract] [FREE Full Text]  



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