European Heart Journal Advance Access published online on June 12, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn275
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org
Smokers paradox or not in heart failure. Just quit
1 Department of Medicine (Cardiology) and Department of Epidemiology and Biostatistics, London Health Sciences Centre/University of Western Ontario, 339 Windermere Rd, London, Ontario N6A 5A5, Canada
2 Faculty of Medicine, University of Ottawa, Ottawa, Canada
3 Division of Prevention and Rehabilitation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, K1Y 4W7, Canada
4 Department of Psychology, University of Western Ontario, Ontario, Canada
5 Cardiac Rehabilitation and Secondary Prevention Program, London Health Sciences Centre, Ontario, Canada
* Corresponding author. Tel: + 1 519 663 3488, Fax: + 1 519 663 3583, Email: nsuskin@uwo.ca
This editorial refers to A smoker's paradox in patients hospitalized for heart failure: findings from OPTIMIZE-HF, by G.C. Fonarow et al. doi:10.1093/eurheartj/ehn210
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Fonarow et al. have explored the smoker's paradox in a novel inception cohort of hospitalized heart failure patients included in the OPTIMIZE-HF registry, by determining the impact of current or recent smoking on outcomes during hospitalization and in the first 60–90 day period following hospital discharge.1 Adjustments for known important potential confounders were performed. Smokers were more likely to have left ventricular systolic dysfunction (59 vs. 51%), were more likely to be male (61 vs. 46%), and had higher B-type natriuretic peptide (BNP) levels (895 vs. 789 pg/mL). However, smokers were much younger (63 vs. 75 years of age), were less likely to have a previous history of heart failure admission (84 vs. 89%),
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- A smoker's paradox in patients hospitalized for heart failure: findings from OPTIMIZE-HF
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EHJ 2008 29: 1983-1991.[Abstract] [FREE Full Text]
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G. C. Fonarow Smoker's paradox in heart failure: might asymmetric dimethylarginine be the possible explanation?: reply Eur. Heart J., December 1, 2008; 29(23): 2949 - 2949. [Full Text] [PDF] |
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