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European Heart Journal Advance Access published online on June 26, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn306
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Hypertension in aortic valve stenosis—a Trojan horse

Jens J. Kaden* and Dariusch Haghi

First Department of Medicine (Cardiology), University Hospital Mannheim, University of Heidelberg, Germany

* Corresponding author. Tel: +49 621 383 2204, Fax: +49 621 383 3821, Email: jens.kaden@med.ma.uni-heidelberg.de

This editorial refers to ‘Systemic pressure does not directly affect pressure gradient and valve area estimates in aortic stenosis in vitro’ by J. Mascherbauer et al., doi:10.1093/eurheartj/ehn209

The first 10% of the full text of this article appears below.

Aortic valve stenosis (AS) is the most frequent heart valve disease in the elderly population,1 causing a significant economic burden on Western societies. Many studies have addressed the prevalence of various cardiovascular risk factors in patients with AS, some of them suggesting possible therapeutic strategies to slow down disease progression.2 Among others, arterial hypertension has been shown to be more frequent in patients with AS than in the control populations without relevant valve disease.3 There has been discussion on how arterial hypertension might influence the aortic valve area and the transvalvular pressure gradient. Theoretically, an elevated blood pressure might lead to an increase in the . . . [Full Text of this Article]


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Systemic pressure does not directly affect pressure gradient and valve area estimates in aortic stenosis in vitro
Julia Mascherbauer, Christina Fuchs, Martin Stoiber, Heinrich Schima, Elisabeth Pernicka, Gerald Maurer, and Helmut Baumgartner
EHJ 2008 29: 2049-2057. [Abstract] [FREE Full Text]