Skip Navigation



European Heart Journal Advance Access published online on August 1, 2008
European Heart Journal, doi:10.1093/eurheartj/ehn343
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
29/17/2067    most recent
ehn343v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in EHJ
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Goette, A.
Right arrow Articles by Braun-Dullaeus, R. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Goette, A.
Right arrow Articles by Braun-Dullaeus, R. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Atrial fibrillation is associated with impaired cognitive function and hippocampal atrophy: silent cerebral ischaemia vs. Alzheimer's disease?

Andreas Goette* and Ruediger C. Braun-Dullaeus

Division of Cardiology, University Hospital Magdeburg, D-39120 Magdeburg, Germany

* Corresponding author. Tel: + 49 391 6713225, Fax: +49 391 6713202, Email: andreas.goette@medizin.uni-magdeburg.de

This editorial refers to ‘Atrial fibrillation in stroke-free patients is associated with memory impairment and hippocampal atrophy,’ by S. Knecht et al. doi:10.1093/eurheartj/ehn341.

The first 10% of the full text of this article appears below.

Atrial fibrillation (AF) is the most common cause of thromboembolic stroke. Several studies have shown an activation of the plasmatic and cellular clotting system in patients with AF.1,2 Interestingly, these changes occur within hours after initiation of AF. In order to predict the individual risk for AF-related thromboembolic events, the CHADS2-score has been developed.1 It takes into account that especially elderly patients, patients with diabetes, hypertension, heart failure, and/or previous stroke are at greatest risk. Depending on the CHADS2-score, the yearly risk of stroke may vary between 1.9% (CHADS2-score of 0) and 18.2% (CHADS2-score of 6). The pathophysiological basis of how these clinical risk factors affect cardiac thrombogenesis or predict future thromboembolic events is complex. According to the Virchow triad there are three determinants of thrombus . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in EHJ:

Atrial fibrillation in stroke-free patients is associated with memory impairment and hippocampal atrophy
Stefan Knecht, Christian Oelschläger, Thomas Duning, Hubertus Lohmann, Johannes Albers, Christoph Stehling, Walter Heindel, Günter Breithardt, Klaus Berger, E. Bernd Ringelstein, Paulus Kirchhof, and Heike Wersching
EHJ 2008 29: 2125-2132. [Abstract] [FREE Full Text]