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European Heart Journal Advance Access originally published online on March 23, 2007
European Heart Journal 2007 28(7):785-787; doi:10.1093/eurheartj/ehm040
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© The European Society of Cardiology 2007. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Reflections on wave reflections in chronic thromboembolic pulmonary hypertension

Robert Naeije* and Sandrine Huez

Department of Cardiology, Erasme University Hospital, Brussels, Belgium

* Corresponding author. Department of Physiology, Erasme Campus CP 604, 808 Lennik road, Brussels B-1070, Belgium. Tel: +32 2 5553322; fax: +32 2 5554124. E-mail address: ernaeije@ulb.ac.be

This editorial refers to ‘A novel echocardiographic predictor of in-hospital mortality and mid-term haemodynamic improvement after pulmonary endarterectomy for chronic thrombo-embolic pulmonary hypertension’{dagger} by M. Hardziyenka et al., on page 842

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Chronic thromboembolic pulmonary hypertension (CTEPH) is a surgically curable form of severe pulmonary hypertension.1 However, in ~10% of the patients, the procedure may not be successful, because of persistent pulmonary hypertension after removal of proximally located thromboembolic material. This complication is of particularly poor prognosis. In the present issue of the European Heart Journal, Hardziyenka et al. report on its prediction by the analysis of Doppler pulmonary arterial waves.2 The authors defined a time to notching expressed as a notch ratio (NR), or the ratio of time from onset of flow to maximum flow deceleration to time from maximum flow deceleration to end of flow. This NR was found to be associated with in-hospital mortality and increased systolic pulmonary artery pressure at 3 months. The authors explain these results by the effects . . . [Full Text of this Article]


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