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European Heart Journal Advance Access originally published online on January 29, 2008
European Heart Journal 2008 29(6):695-697; doi:10.1093/eurheartj/ehm643
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Epicardial adipose tissue: friendly companion or hazardous neighbour for adjacent coronary arteries?

Nithima Chaowalit1 and Francisco Lopez-Jimenez2,*

1 Division of Cardiology, Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
2 Division of Cardiovascular Diseases, Mayo Clinic and Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA

* Corresponding author. Tel. +1 507 284 8087, Fax: +1 507 266-3623. Email: lopez@mayo.edu

This editorial refers to ‘Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women’{dagger} by A.M. de Vos et al. on page 777

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The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 10% of the full text of this article appears below.

Visceral adiposity has been increasingly recognized as a marker for cardiovascular risk and metabolic syndrome, including glucose intolerance, hypertension, dyslipidaemia, hyperinsulinaemia, and atherosclerosis. The pathophysiology may be explained by its action as an endocrine and paracrine organ with various biological and metabolic functions, including a reservoir for several atherogenic inflammatory cytokines.1,2 Visceral adipose tissue expresses numerous genes for secretory proteins, and several biologically active molecules secreted from adipose tissue (adipocytokines) may have important roles in the development of atherosclerotic diseases.

Epicardial adipose tissue (EAT) is a particular form of visceral adipose tissue deposited around the heart and found in considerable quantities around subepicardial coronary arteries. EAT shares a common embryological origin . . . [Full Text of this Article]


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Related articles in EHJ:

Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women
Alexander M. de Vos, Mathias Prokop, Cornelis J. Roos, Matthijs F.L. Meijs, Yvonne T. van der Schouw, Annemarieke Rutten, Petra M. Gorter, Maarten-Jan Cramer, Pieter A. Doevendans, Benno J. Rensing, Marie-Louise Bartelink, Birgitta K. Velthuis, Arend Mosterd, and Michiel L. Bots
EHJ 2008 29: 777-783. [Abstract] [Full Text]