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European Heart Journal Advance Access originally published online on June 5, 2008
European Heart Journal 2008 29(13):1600-1602; doi:10.1093/eurheartj/ehn238
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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

Non-invasive risk stratification in hypertrophic cardiomyopathy: don't throw out the baby with the bathwater

Srijita Sen-Chowdhry1,2 and William J. McKenna1,*

1 The Heart Hospital, University College London Hospitals NHS Trust and Institute of Cardiovascular Science, London, UK
2 Imperial College, London, UK

* Corresponding author. Tel: +44 2075738841, Fax: +44 2075738859, Email: william.mckenna@uclh.org

This editorial refers to ‘Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy’{dagger} by R.C. Saumarez et al., on page 1653

Footnotes

The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.

The first 150 words of the full text of this article appear below.

Although historical accounts consistent with sudden cardiac death (SCD) date back to ancient times, only in the past quarter of a century has prevention of these events become possible. Growing understanding of underlying disease states, development of effective anti-arrhythmic therapy, and the advent of the implantable cardioverter-defibrillators (ICDs) have all contributed to realization of this goal. Nevertheless, prophylactic ICD placement in the inherited cardiovascular disease population to some extent represents a double-edged sword. On the one hand, averting SCD in individuals without debilitating symptoms or co-morbidities may yield an exceptional number of quality-adjusted life years. Conversely, the present knowledge gap regarding the consequences of extended device therapy is of particular relevance in young patients in whom the aim is to achieve normal life expectancy. Increasing . . . [Full Text of this Article]


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Related articles in EHJ:

Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy
Richard C. Saumarez, Mariusz Pytkowski, Maciej Sterlinski, John P. Bourke, Jonathan R. Clague, Stuart M. Cobbe, Derek T. Connelly, Michael J. Griffith, Pascal P. McKeown, Karen McLeod, John M. Morgan, Nicolas Sadoul, Lidia Chojnowska, Christopher L.-H. Huang, and Andrew A. Grace
EHJ 2008 29: 1653-1661. [Abstract] [Full Text]