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Videodensitometric quantitative angiography after coronary balloon angioplasty, compared to edge-detection quantitative angiography and intracoronary ultrasound imaging

R.J.G Peters, W.E.M Kok, G Pasterkamp, C Von Birgelen, M Prins, P.W Serruys
DOI: http://dx.doi.org/10.1053/euhj.1999.1853 654-661 First published online: 2 April 2000


Aims To assess the value of videodensitometric quantification of the coronary lumen after angioplasty by comparison to two other techniques of coronary artery lumen quantification.

Methods and Results Videodensitometric quantitative angiography, edge detection quantitative angiography and 30MHz intracoronary ultrasound imaging were performed after successful balloon angioplasty in 161 patients. Lumen cross-sectional areas were mean (SD) 2·82 (1·15)mm2for edge detection quantitative angiography, 3·67 (1·5)mm2for videodensitometric quantitative angiography and 5·32 (1·75)mm2for intracoronary ultrasound imaging (P<0·001). The correlation between intracoronary ultrasound imaging and videodensitometric quantitative angiography (r=0·44) was almost similar to that of intracoronary ultrasound imaging and edge detection quantitative angiography (r=0·47). The correlation between the three techniques was not significantly influenced by the presence of ruptures and dissections on intracoronary ultrasound imaging. The absence of calcifications improved the correlation between videodensitometry and intracoronary ultrasound imaging.

Conclusions The luminal dimensions as measured by videodensitometric quantitative angiography matched intracoronary ultrasound imaging derived dimensions more closely than edge detection quantitative angiography. Videodensitometric quantitative angiography represents an on-line alternative to intracoronary ultrasound imaging for quantitative analysis regardless of the degree of vessel damage.

  • Videodensitometry, quantitative coronary angiography, intravascular ultrasound imaging, balloon angioplasty